This Creamy Cajun Salmon Penne with Spinach is a bold and flavorful pasta dish combining tender Cajun-spiced salmon with a rich Parmesan cream sauce and fresh spinach. Ready in just 30 minutes, it’s a restaurant-quality meal perfect for weeknights or special occasions!

Why You’ll Love This Recipe

Packed with flavor: Cajun spices and creamy sauce create a tantalizing balance.
Healthy twist: Salmon and spinach add a boost of nutrients and omega-3s.

Quick and easy: A gourmet dinner ready in just half an hour.
Versatile: Works with other proteins like chicken or shrimp.
Impressive yet simple: Great for casual dinners or entertaining guests.

Ingredients

(Tip: You can find the complete list of ingredients and their measurements in the recipe card below.)

300g penne pasta
2 salmon fillets, skinless

1 tablespoon olive oil
1 teaspoon smoked paprika
1 teaspoon garlic powder

1 teaspoon onion powder
1/2 teaspoon cayenne pepper
1/2 teaspoon dried thyme

1/2 teaspoon dried oregano
Salt and pepper to taste
1 tablespoon butter

3 garlic cloves, minced
1 cup heavy cream
1/2 cup grated Parmesan cheese

2 cups fresh spinach, chopped
1/2 teaspoon paprika for garnish (optional)

Directions

Cook the pasta: Bring a large pot of salted water to a boil and cook the penne according to package instructions. Drain and set aside.

Season the salmon: Rub the salmon fillets with smoked paprika, garlic powder, onion powder, cayenne pepper, thyme, oregano, salt, and pepper.
Cook the salmon: Heat olive oil in a skillet over medium heat. Add the salmon and cook for 3-4 minutes per side, or until cooked through. Remove from the skillet and set aside.
Make the sauce: In the same skillet, melt the butter over medium heat. Add the minced garlic and sauté for 1-2 minutes until fragrant.

Prepare the cream sauce: Pour the heavy cream into the skillet, scraping up any browned bits from the pan. Stir in the grated Parmesan cheese until the sauce is smooth and creamy.
Add spinach: Stir in the chopped spinach and let it wilt in the sauce for 1-2 minutes.
Combine pasta and sauce: Toss the cooked penne in the sauce, ensuring the pasta is well coated.

Flake and add salmon: Flake the cooked salmon into bite-sized pieces and gently fold it into the pasta.
Serve: Garnish with a sprinkle of paprika (optional) and serve warm.

Servings and Timing

Prep Time: 10 minutes

Cooking Time: 20 minutes
Total Time: 30 minutes
Servings: 4

Variations

Swap proteins: Use chicken, shrimp, or tofu instead of salmon.
Make it spicy: Increase the cayenne pepper or add a dash of hot sauce to the sauce.
Cheese options: Substitute Parmesan with Pecorino Romano or a cheese blend.

Vegetarian option: Omit the salmon and add more spinach or mushrooms.
Gluten-free: Use gluten-free pasta to suit dietary needs.

Storage/Reheating

Storage: Store leftovers in an airtight container in the refrigerator for up to 2 days.

Reheating: Warm in a skillet over low heat, adding a splash of cream or milk to maintain the sauce’s texture. Alternatively, microwave individual portions for 1-2 minutes.
Freezing: Not recommended, as the cream sauce may separate upon thawing.

FAQs

Can I use frozen salmon?

Yes, thaw the salmon fillets completely and pat them dry before seasoning.

What’s the best type of pasta for this dish?

Penne is great, but fettuccine, rigatoni, or bow-tie pasta also work well.

Can I make this ahead of time?

While it’s best served fresh, you can prepare the sauce and cook the salmon in advance, then reheat and combine with freshly cooked pasta.

How do I ensure the salmon doesn’t overcook?

Cook the salmon over medium heat and check for doneness with a fork—it should flake easily.

What other vegetables can I add?

Bell peppers, cherry tomatoes, or mushrooms are great additions.

Is this dish suitable for meal prep?

Yes, portion it into individual containers for easy reheating, but avoid overcooking the salmon.

How can I make the sauce thicker?

Let the sauce simmer for a few extra minutes or add a touch more Parmesan.

Can I use milk instead of heavy cream?

Heavy cream provides a richer sauce, but you can use whole milk with a bit of cornstarch for a lighter option.

What can I serve alongside this dish?

Pair with a simple green salad or garlic bread for a complete meal.

Can I use store-bought Cajun seasoning?

Absolutely! Replace the individual spices with 1-2 teaspoons of pre-made Cajun seasoning.

Conclusion

Creamy Cajun Salmon Penne with Spinach is a vibrant, flavorful dish that’s both comforting and nutritious. Perfect for quick weeknight dinners or impressing guests, this recipe is easy to prepare and endlessly satisfying. Give it a try, and enjoy a taste of indulgence in every bite!